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Purified Anti-Human CD15 Monoclonal Antibody
The CD15 (HI98) antibody recognizes a 220-kDa carbohydrate antigen–Lacto–N–fucopentaose III, also called Lewis X, X-hapten, and SSEA-I. CD15 antigen is expressed on mature granulocytes (strongly), monocytes (weakly), immature bone marrow cells of myelomonocytic lineage, peripheral blood T lymphocytes (weakly), and some T-cells. CD15 antigen is also expressed on leukemia cells of myelomonocytic origin, Langerhans cells, a variety of carcinoma cells (preferentially adenocarcinomas), and occasionally on lymphocytic leukemia cells. CD15 is absent from B lymphocytes, erythrocytes and platelets. A soluble form of CD15 exists in serum (plasma) besides a membrane form. CD15 antigen plays a role in mediating phagocytosis, bactericidal activity and chemotaxis.
FCM
Human
Liquid
Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.
PBS pH 7.2, 0.09% NaN3, 0.2% BSA
Mouse IgM
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used from 20 µL to 5 µL per 100 µL of peripheral blood. Please check your vial). Since applications vary, the appropriate dilutions must be determined for individual use.
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