概述

产品名称：LE/AF Purified Anti-Mouse LPAM-1 Monoclonal Antibody

描述：DATK32 antibody is specific for a combinatorial determinate of integrin α4β7complex. Integrin α4β7 is composed of a 150 kD (α4 or CD49d) and a 130 kD (β7) heterodimer, also known as CD49d/β7 or LPAM-1. Belonging to the Ig superfamily, it is found on the majority of peripheral lymphocytes and subsets of thymocytes and bone marrow cells (including mast cell progenitors). Integrin α4β7 binds its ligands, VCAM-1 (CD106), MAdCAM-1 and fibronectin, and plays an important role in lymphocytes adhesion and the direction of migration of blood lymphocytes to the intestine and associated lymphoid tissues.

应用范围：FCM,IHC,IP

种属反应性：Mouse

性能

形态：Liquid

存储条件：Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.

存储溶液：PBS, pH 8.0

纯度：1mg/ml, >95% (by SDS-PAGE)

亚型：Rat IgG2a

应用

应用说明：This DAKT32 antibody has been reported for use in flow cytometric staining, immunoprecipitation and immunohistochemical staining of frozen sections.