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LE/AF Purified Anti-Mouse CD210 Monoclonal Antibody
CD210 is a 90-110 kD IL-10 receptor. It is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Ligand binding of CD210 induces Jak1 and Tyk, resulting in STAT1 and STAT3 activation. IL-10 receptor stimulation results in the inhibition of cytokine production and the costimulation of B cell proliferation and differentiation. The only known ligand for this receptor is IL-10.
FCM,Block
Mouse
Liquid
Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Rat IgG1
This 1B1.3A antibody has been reported for use in flow cytometric staining. Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking of ligand binding.
IL-10R
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