概述

产品名称：LE/AF Purified Anti-Mouse CD273 Monoclonal Antibody

描述：B7-DC is also called programmed death ligand 2 (PDL2). It has recently been clustered as CD273. This ligand is a 42 kD member of the immunoglobulin receptor superfamily expressed on a subset of dendritic cells, liver and a small subset of macrophages as well as a few transformed cell lines. CD273 has been reported to be stimulatory on dendritic cells when cross-linked and to inhibit T cell activation upon engaging the PD-1 receptor. CD273 has also been reported to bind to an alternative receptor and to mediate T cell activation through such non-PD1 mediated interactions. The TY25 antibody has been reported to be useful for blocking PD-1 mediated interactions.

应用范围：FCM,Block,IHC,IP,WB

种属反应性：Mouse

性能

形态：Liquid

存储条件：Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.

存储溶液：PBS, pH 7.2

纯度：1mg/ml, >95% (by SDS-PAGE)

亚型：Rat IgG2a

应用

应用说明：This TY25 antibody has been reported for use in flow cytometric staining. Additional reported applications (for the relevant formats) include: immunoprecipitation, Western blotting blocking of PD-1 mediated interactions, and immunohistochemistry of acetone-fixed frozen sections.

别名：PD-L2