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LE/AF Purified Anti-Mouse CD183 Monoclonal Antibody CXCR3 M11831-14Fdatasheet

数据表

  • 概述

    LE/AF Purified Anti-Mouse CD183 Monoclonal Antibody

    CD183, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes, or granulocytes.

    FCM,Block

    Mouse

  • 性能

    Liquid

    Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.

    PBS, pH 7.2

    1mg/ml, >95% (by SDS-PAGE)

    Hamster IgG

  • 应用

    CXCR3