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LE/AF Purified Anti-Mouse CD154 Monoclonal Antibody
CD154 is a 39 kD TNF superfamily member also known as CD40 ligand, gp39, T-BAM, TRAP, and Ly-62. CD154 is an accessory molecule expressed predominantly on activated CD4+ lymphocytes that bind CD40. CD154 plays an important role in T-B cell costimulation. The MR1 antibody has been reported to inhibit the activation of T and B lymphocytes in vitro and antigen-specific lymphocyte responses in vivo.
FCM,IHC,Block
Mouse
Liquid
Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Hamster IgG
This MR1 antibody has been reported for use in flow cytometric staining. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections, and in vitro and in vivo blocking of ligand binding.
CD40L
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