首页 > 产品 > 流式抗体 > 抗小鼠抗体

PerCP Anti-Mouse CD8a Monoclonal Antibody 53.6.7 M10081-32Adatasheet

推荐产品

  • APC Anti-Mouse CD11b Monoclonal Antibody Mac-1 M1/70 M10117-11C

数据表

  • 概述

    PerCP Anti-Mouse CD8a Monoclonal Antibody

    CD8, also known as Lyt-2, Ly-2, or T8, consists of disulfide-linked α and β chains that form the α(CD8a)/β(CD8b) heterodimer and α/α homodimer. CD8a is a 34 kD protein that belongs to the immunoglobulin family. The CD8 α/β heterodimer is expressed on the surface of most thymocytes and a subset of mature TCR α/β T cells. CD8 expression on mature T cells is non-overlapping with CD4. The CD8 α/α homodimer is expressed on a subset of γ/δ TCR-bearing T cells, NK cells, intestinal intraepithelial lymphocytes, and lymphoid dendritic cells. CD8 is an antigen co-receptor on T cells that interacts with MHC class I on antigen-presenting cells or epithelial cells. CD8 promotes T cell activation through its association with the TCR complex and protein tyrosine kinase lck.

    FCM

    Mouse

    Rat

  • 性能

    liquid

    Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

    PBS pH 7.2, 0.09% NaN3, 0.2% BSA

    0.2 mg/ml

    53.6.7

    Rat lgG2a

  • 应用

    Recommended Application: FC

    Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ≤ 0.25 µg /10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.

  • 图像
    PerCP Anti-Mouse CD8a Monoclonal Antibody.jpg
    C57BL/6 mouse splenocytes stained with PerCP anti-mouse CD8a and FITC anti-mouse CD3ε.