概述

产品名称：PE Anti-Mouse CD80(B7-1) Monoclonal Antibody

描述：CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

应用范围：FCM

种属反应性：Mouse

免疫原：Hamster

性能

形态：liquid

存储条件：Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

存储溶液：PBS pH 7.2, 0.09% NaN3, 0.2% BSA

纯度：0.2 mg/ml

克隆：16-10A1

亚型：Hamster IgG

应用

应用说明：Recommended Application: FC

功能：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysi s(The amount of the reagent is suggested to be used ≤ 0.5 µg /10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.

别名：B7-1

图像

PE Anti-Mouse CD80-B7-1- Monoclonal Antibody.jpg

LPS (3-day) stimulated C57BL/6 mouse splenocytes stained with PE anti-mouse CD80.