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LE/AF Purified Anti-Human CD4 Monoclonal Antibody H10041-14Bdatasheet

数据表

  • 概述

    LE/AF Purified Anti-Human CD4 Monoclonal Antibody

    CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. The OKT4 antibody binds to the D3 domain of CD4 and does not block HIV binding.

    FCM,IHC

    Human

  • 性能

    Liquid

    Keep as concentrated solution.Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Whenever possible avoid freeze/thaw cycles

    PBS, pH 7.2

    1mg/ml, >95% (by SDS-PAGE)

    Mouse IgG2b

  • 应用

    This OKT-4 antibody has been reported for use in Flow Cytometric Analysis, Immunohistochemical Staining of Frozen Tissue Sections.