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LE/AF Purified Anti-Human CD40 Monoclonal Antibody
CD40 is a 48 kD type I glycoprotein also known as BP50. It is a member of the TNFR superfamily primarily expressed on B cells, macrophages, follicular dendritic cells, endothelial cells, fibroblasts, and at low levels on plasma cells. CD40 has been reported to be involved in B cell differentiation, costimulation, isotype class-switching, and protection from apoptosis. Additionally, CD40 is important for T cell-B cell interactions. The ligand of CD40 is CD154 (CD40 ligand). The G28.5 antibody has been reported to promote B cell proliferation in the presence of anti-IgM, IL-4 or PMA.
FCM,Block,WB,IF
Human
Liquid
Keep as concentrated solution.Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Whenever possible avoid freeze/thaw cycles.
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Mouse IgG1
This G28.5 antibody has been reported for use in Flow Cytometric Analysis, Western Blotting, Immunofluorescence Microscopy and Functional Assay.
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