概述

产品名称：Purified Anti-Human CD29 Monoclonal Antibody

描述：The CD29 (HI29a) antibody recognizes the 130-kDa transmembrane glycoprotein integrin β1 subunit which is the common β1 chain of the very late antigen (VLA) forming a non-covalent heterodimeric complex with several integrins α subunits that are receptors for extracellular matrix proteins such as collagen, fibronectin and osteopontin. CD29 hasa broad tissue distribution including lymphocytes, monocytes, platelets,fibroblasts, and endothelial cells, whereas it is weakly expressed in granulocytes and absent in erythrocytes. CD29 is an important adhesion molecule involved in cell-cell and cell-extracellular matrix interactions.CD29 plays a critical role in the functional activity of lymphocytes by influencing cellular migration patterns as well as by transducing intracellular signals that influence lymphocyte function.

应用范围：FCM

种属反应性：Human

性能

形态：Liquid

存储条件：Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid cycles of freezing and thawing.

存储溶液：PBS pH 7.2 with 0.09%NaN3

亚型：Mouse IgG1

应用

应用说明：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Since applications vary, the appropriate dilutions must be determined for individual use.