登录 | 注册 | 购物车 | 帮助中心 | English Vision
022-58105045
LE/AF Purified Anti-Mouse CD80 Monoclonal Antibody
CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
FCM,IHC,IP,Block
Mouse
Liquid
Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Hamster IgG
This 16-10A1 antibody has been reported for use in immunoprecipitation, in vitro and in vivo blocking of CTLA-4 Ig to CD80 by blocking costimulation of T cells by activated B cells, and immunohistochemical staining of acetone-fixed frozen sections.
B7-1
在中国,您可以从天津三箭和我们的授权经销商处购买天津三箭的产品或获得技术支持。
联系电话:022-66211636
400-621-0003