概述

产品名称：PE Anti-Human CD16 (CB16) Monoclonal Antibody

描述：CD16 is known as low affinity IgG receptor III (FcγRIII). It is expressed as two distinct (CD16a and CD16b) forms. CD16a (FcγRIIIA) is a 50-65 kD polypeptide-anchored transmembrane protein. It is expressed on the surface of NK cells, activated monocytes, macrophages, and placental trophoblasts in humans.CD16b (FcγRIIIB) is a 48 kD glycosylphosphatidylinositol (GPI)-anchored protein. It is over 95% homologous to CD16a in
extracellular domain and is expressed specifically on neutrophils.CD16 binds aggregated IgG or IgG-antigen complex that functions in NK cell activation, phagocytosis, and antibody-dependent cellmediated cytotoxicity (ADCC). 

应用范围：FCM

种属反应性：Human

性能

形态：liquid

存储条件：Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

存储溶液：PBS pH 7.2, 0.09% NaN3, 0.2% BSA

克隆：CB16

亚型：Mouse IgG1

应用

应用说明：Recommended Application: FC

功能：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used from 20 µL to 5 µL per 100 µL of peripheral blood. Please check your vial). Since applications vary, the appropriate dilutions must be determined for individual use.

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