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Purified Anti-Human CD14 Monoclonal Antibody
CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens and in the upregulation of adhesion molecules and cytokines expression in monocytes and neutrophils.
FCM
Human
Liquid
Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid cycles of freezing and thawing.
0.01 M PBS, pH 7.0 with 0.09% NaN3
Mouse IgM
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Since applications vary, the appropriate dilutions must be determined for individual use.
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