概述

产品名称：Purified Anti-Human CD8 Monoclonal Antibody

描述：CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the α3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck.

应用范围：FCM

种属反应性：Human

性能

形态：Liquid

存储条件：Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid cycles of freezing and thawing.

存储溶液：PBS pH 7.2 with 0.09% NaN3

亚型：Mouse IgG1

应用

应用说明：This HIT8a antibody has been reported for use in Flow Cytometric Analysis and Immunohistochemical Staining. Since applications vary, the appropriate dilutions must be determined for individual use.