概述

描述：Human thyroglobulin (hTG) is a high molecular weight glycoprotein (605 kDa) found in the thyroid follicular cells. It plays a central role in the uptake, incorporation, and regulated biosynthesis of thyroid hormones. Anti-thyroglobulin reacts with human thyroglobulin as demonstrated by a single band of immunoblotting in a lysate of human thyroid tissue. The vast majority of follicular carcinomas of the thyroid will give positive immunoreactivity for anti-thyroglobulin even though sometimes only focally. Poorly differentiated carcinomas of the thyroid are frequently anti-thyroglobulin negative.Adenocarcinomas of other-than-thyroid origin do not react with this antibody.

应用范围：IHC

种属反应性：Human

免疫原：Human thyroglobulin

性能

形态：Liquid

存储条件：Thyroglobulin antibody is stable for 1 month at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

存储溶液：PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol

纯度：0.2 mg/ml

亚型：Mouse IgG

应用

应用说明：IHC: 1:200-1:500 Optimal dilutions/concentrations should be determined by the end user.

图像

Thyroglobulin mouse monoclonal antibody.jpg

immunohistochemistry Staining of follicular thyroid carcinoma with thyroglobulin mouse mAb