概述

产品名称：Anti-human CK19 mouse monoclonal antibody

描述：This protein is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelia cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which aare arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. Keratin 19 is not expressed in hepatocytes, therefore, antibody to keratin 19 is useful in the identification of liver metastasis. The degree of keratin 19 positivity in breast cancer distinguishes malignant from begin tumours. Keratin 19 is often co-expressed with keratin 7.

应用范围：IHC

种属反应性：Human

免疫原：Recombinant protein of human CK19

性能

形态：Liquid

存储条件：CK19 antibody is stable for 1 month at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

存储溶液：PBS, pH 7.4, containing 0.02% sodium azide and 50% glycerol

纯度：0.2 mg/ml

亚型：Mouse IgG

应用

应用说明：IHC: 1/250-1/500 Optimal dilutions/concentrations should be determined by the end user.

图像

CK19 mouse mAb.jpg

Immunohistochemistry Staining of Human colon cancer with CK19 mouse mAb