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LE/AF Purified Anti-Human CD62L Monoclonal Antibody L-Selectin H10623-14Fdatasheet

数据表

  • 概述

    LE/AF Purified Anti-Human CD62L Monoclonal Antibody

    CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

    Block,FCM,IHC,WB

    Human

  • 性能

    Liquid

    Keep as concentrated solution.Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Whenever possible avoid freeze/thaw cycles.

    PBS, pH 7.2

    1mg/ml, >95% (by SDS-PAGE)

    Mouse IgG1

  • 应用

    This DREG56 antibody has been reported for use in Flow Cytometric Analysis, Western Blotting and Blocking.

    L-Selectin