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LE/AF Purified Anti-Human CD3 Monoclonal Antibody
CD3ε is a 20 kD chain of the CD3/T-cell receptor (TCR) complex which is composed of two CD3ε, one CD3γ, one CD3δ, one CD3ζ (CD247), and a T-cell receptor (α/β or γ/δ) heterodimer. It is found on all mature T lymphocytes, NK-T cells, and some thymocytes. CD3, also known as T3, is a member of the immunoglobulin superfamily that plays a role in antigen recognition, signal transduction, and T cell activation. The OKT3 antibody is able to induce T cell activation.
FCM,IP,WB,IHC,Activ
Human
Liquid
Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Mouse IgG1
This UCHT1 antibody has been reported for use in Flow Cytometric Analysis, Immunohistochemical Staining of Frozen Tissue Sections. It has also been reported for use in cell activation, immunoprecipitation and Western blotting.
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