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LE/AF Purified Anti-Mouse IL-10 Monoclonal Antibody
IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production.
FCM,Neut,WB,IF,ELISA,ELISPOT
Mouse
Liquid
Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Rat IgG1
This JES5-2A5 antibody has been reported for use in Western Blotting, Enzyme-linked Immunosorbent Assay, Enzyme-linked Immunosorbent Spot. It has also been reported for use in Cytokine Neutralization.
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