概述

产品名称：APC Anti-Human CD28 Monoclonal Antibody

描述：CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.

应用范围：FCM

种属反应性：Human

免疫原：Mouse

性能

形态：liquid

存储条件：Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

存储溶液：PBS pH 7.2, 0.09% NaN3, 0.2% BSA

克隆：CD28.2

亚型：Mouse IgG1

应用

应用说明：Recommended Application: FC

功能：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used from 20 µL to 5 µL per 100 µL of peripheral blood. Please check your vial). Since applications vary, the appropriate dilutions must be determined for individual use.

图像

APC Anti-Human CD28 Monoclonal Antibody.jpg

Human peripheral blood lymphocytes stained with APC anti-human CD28.