概述

产品名称：Biotin Anti-Mouse TCR Vγ1 Monoclonal Antibody

描述：T cell receptor (TCR) is a heterodimer consisting of an α and β chain (TCR α/β) or a γ and δ chain (TCR γ/δ). TCR associates with CD3 to form a CD3/TCR complex. The CD3/TCR plays a key role in antigen recognition, signal transduction, and T cell activation. TCR Vγ1.1 (Garman nomenclature) is also called TCR Vγ1 (Tonegawa nomenclature). The Vγ1 gene almost exclusively rearranges to the Jγ4-Cγ4 gene. Vγ1- Jγ4-Cγ4 expressing cells constitute a major population of γ/δ T cells in thymus and peripheral lymphoid organs in adult mice, but they are only composed of a minor population of γ/δ T cells during fetal and early postnatal life. Vγ1 T cell development can happen in thymus-dependent and thymus-independent manners.

应用范围：FCM

种属反应性：Mouse

免疫原：Hamster

性能

形态：liquid

存储条件：Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

存储溶液：PBS pH 7.2, 0.09% NaN3, 0.2% BSA

纯度：0.5 mg/ml

克隆：2.11

亚型：Hamster IgG

应用

应用说明：Recommended Application: FC

功能：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ≤ 0.25 µg/10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.

图像

Biotin Anti-Mouse TCR Vγ1 Monoclonal Antibody.jpg

C57BL/6 mouse splenocytes CD3+ stained with APC anti-mouse gdTCR and Biotin anti-mouse TCR Vγ1, followed by PE-SA.