概述

产品名称：Biotin Anti-Mouse TCR Vγ2 Monoclonal Antibody

描述：T-Cell Receptor (TCR) Vγ4 bearing T lymphocytes make up a significant proportion of γδ TCR cells in late fetal and adult peripheral lymphoid tissues. TCR γδ T cells may play a role in immunological surveillance for stress-induced self-antigens. The frequency of Vγ4 expression in different strains varied from 12% to 54% in the TCR γδ repertoire. Variations in the levels of Vγ4+ cells are not associated with MHC haplotype. High Vγ4 expression is influenced by the TCR-δ locus. Expanding Vγ4+ TCRγδ cells in B6 mice overwhelmingly use a Vδ7+ δ chain except in the DBA/2 strain.

应用范围：FCM

种属反应性：Mouse

免疫原：Hamster

性能

形态：liquid

存储条件：Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

存储溶液：PBS pH 7.2, 0.09% NaN3, 0.2% BSA

纯度：0.5 mg/ml

克隆：UC3-10A6

亚型：Hamster IgG

应用

应用说明：Recommended Application: FC

功能：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ≤ 0.25 µg /10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.

图像

Biotin Anti-Mouse TCR Vγ2 Monoclonal Antibody.jpg

C57BL/6 mouse splenocytes CD3+ stained with FITC anti-mouse gdTCR and Biotin anti-mouse TCR Vγ4, followed by PE-SA.