概述

产品名称：APC Anti-Mouse CD152 Monoclonal Antibody

描述：CD152, also known as CTLA-4 or Ly-56, is a 33 kD member of the immunoglobulin superfamily. It is expressed on activated T and B lymphocytes. CD152 is similar to CD28 in amino acid sequence, structure, and genomic organization and these two receptors share common B7 family counter-receptors (B7-1, B7-2). Whereas CD28 delivers a costimulatory signal in T cell activation, CTLA-4 negatively regulates cell-mediated immune responses. CD152 is thought to play a role in the induction and maintenance of immunological tolerance as well as the development of protective immunity and thymocyte regulation.

应用范围：FCM

种属反应性：Mouse

免疫原：Hamster

性能

形态：liquid

存储条件：Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

存储溶液：PBS pH 7.2, 0.09% NaN3, 0.2% BSA

纯度：0.2 mg/ml

克隆：UC10-4F10-11

亚型：Hamster IgG

应用

应用说明：Recommended Application: FC

功能：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ≤ 1.0 µg/10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.

别名：CTLA-4

图像

APC Anti-Mouse CD152 Monoclonal Antibody.jpg

Con A (day-2) stimulated BALB/c splenocytes stained with APC anti-mouse CD152 and PE anti-mouse CD3.