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Biotin Anti-Mouse CD119 Monoclonal Antibody IFN-γR GR-20 M11192-08Bdatasheet

数据表

  • 概述

    Biotin Anti-Mouse CD119 Monoclonal Antibody

    CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

    FCM

    Mouse

    Rat

  • 性能

    liquid

    Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

    PBS pH 7.2, 0.09% NaN3, 0.2% BSA

    0.5 mg/ml

    GR-20

    Rat IgG2a

  • 应用

    Recommended Application: FC

    Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ≤ 0.25 µg /10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.

    IFN-γR

  • 图像
    Biotin Anti-Mouse CD119 Monoclonal Antibody.jpg
    C57BL/6 mouse splenocytes stained with Biotin anti-mouse CD119, followed by PE-SA.