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Biotin Anti-Mouse CD80(B7-1) Monoclonal Antibody B7-1 16-10A1 M10801-08Edatasheet

数据表

  • 概述

    Biotin Anti-Mouse CD80(B7-1) Monoclonal Antibody

    CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

    FCM

    Mouse

    Hamster

  • 性能

    liquid

    Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

    PBS pH 7.2, 0.09% NaN3, 0.2% BSA

    0.5 mg/ml

    16-10A1

    Hamster IgG

  • 应用

    Recommended Application: FC

    Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysi s(The amount of the reagent is suggested to be used ≤ 0.25 µg /10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.

    B7-1

  • 图像
    Biotin Anti-Mouse CD80-B7-1- Monoclonal Antibody.jpg
    LPS (3-day) stimulated C57BL/6 mouse splenocytes stained with Biotin anti-mouse CD80, followed by PE-SA.