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PE Anti-Mouse CD40 Monoclonal Antibody FGK4.5 M10401-09Bdatasheet

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数据表

  • 概述

    PE Anti-Mouse CD40 Monoclonal Antibody

    CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154(gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

    FCM

    Mouse

    Rat

  • 性能

    liquid

    Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

    PBS pH 7.2, 0.09% NaN3, 0.2% BSA

    0.2 mg/ml

    FGK4.5

    Rat IgG2a

  • 应用

    Recommended Application: FC

    Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ≤ 1 µg/10^6 cells in 100 µl). Since applications vary, the appropriate dilutions must be determined for individual use.

  • 图像
    PE Anti-Mouse CD40 Monoclonal Antibody.jpg
    C57BL/6 mouse splenocytes stained with FITC anti-mouse CD3 and PE anti-mouse CD40.