概述

产品名称：LE/AF Purified Anti-Mouse/Human CD44 Monoclonal Antibody

描述：CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid-levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.

应用范围：FCM,ELISA,IHC,IP, C',Stim

种属反应性：Mouse

性能

形态：Liquid

存储条件：Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.

存储溶液：PBS, pH 7.2

纯度：1mg/ml, >95% (by SDS-PAGE)

亚型：Rat IgG2b

应用

应用说明：This IM7 antibody has been reported for use in Enzyme-linked Immunosorbent Assay, Immunohistochemical, Immunoprecipitation and Flow Cytometric Analysis. It has also been reported for use in cell stimulation and Complement Mediated Cell Depletion.