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LE/AF Purified Anti-Mouse CD11b(Mac-1) Monoclonal Antibody
CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, or Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.
FCM,IP, Block,IF,Deplete,IHC
Mouse
Liquid
Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid cycles of freezing and thawing
PBS, pH 7.2
1mg/ml, >95% (by SDS-PAGE)
Rat IgG2b
This M1/70 antibody has been reported for use in Flow Cytometric Analysis, Immunohistochemical Staining of Frozen Tissue Sections, Immunoprecipitation, Immunofluorescence Microscopy. It has also been reported for use in cell depletion.
Mac-1
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