概述

产品名称：LE/AF Purified Anti-Mouse CD11a Monoclonal Antibody

描述：CD11a is a 180 kD glycoprotein, also known as αL integrin, LFA-1 α, Ly-15, or Ly-21. It is a member of the integrin family, primarily expressed on lymphocytes, monocytes/macrophages, and granulocytes. In association with CD18, the CD11a/CD18 complex forms LFA-1. CD11a plays an important role in intercellular adhesion and costimulation by binding its ligands, ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

应用范围：FCM

种属反应性：Mouse

性能

形态：Liquid

存储条件：Keep as concentrated solution.Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.

存储溶液：PBS, pH 7.2

纯度：1mg/ml, >95% (by SDS-PAGE)

亚型：Rat IgG1

应用

应用说明：The M17/4 antibody can block CD11a-mediated cellular adhesion. Additional reported applications of this antibody (for the relevant formats) include: immunoprecipitation, in vitro blocking of cell-cell adhesion and FOXP3 expression, and immunohistochemical staining of acetone-fixed frozen sections.