概述

产品名称：Biotin Anti-Human CD4 (OKT-4) Monoclonal Antibody

描述：CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. The OKT4 antibody binds to the D3 domain of CD4 and does not block HIV binding.

应用范围：FCM

种属反应性：Human

免疫原：Mouse

性能

形态：liquid

存储条件：Keep as concentrated solution. Store at 4°C and protected from prolonged exposure to light. Do not freeze.

存储溶液：PBS pH 7.2, 0.09% NaN3, 0.2% BSA

纯度：0.5 mg/ml

克隆：OKT-4

亚型：Mouse IgG2b

应用

应用说明：Recommended Application: FC

功能：Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis (The amount of the reagent is suggested to be used ≤ 1.0 µg /10^6 cells in 100 µl.). Since applications vary, the appropriate dilutions must be determined for individual use.

图像

Biotin Anti-Human CD4 -OKT-4- Monoclonal Antibody.jpg

Human peripheral blood lymphocytes stained with Biotin anti-human CD4, followed by PE-SA and FITC anti-human CD3.