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LE/AF Purified Anti-Mouse TCR Vγ1 Monoclonal Antibody M100T1-14Edatasheet

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数据表

  • 概述

    LE/AF Purified Anti-Mouse TCR Vγ1 Monoclonal Antibody

    T cell receptor (TCR) is a heterodimer consisting of an α and β chain (TCR α/β) or a γ and δ chain (TCR γ/δ). TCR associates with CD3 to form a CD3/TCR complex. The CD3/TCR plays a key role in antigen recognition, signal transduction, and T cell activation. TCR Vγ1 (Tonegawa nomenclature) is also called TCR Vγ1.1 (Garman nomenclature). The Vγ1 gene almost exclusively rearranges to the Jγ4-Cγ4 gene. Vγ1- Jγ4-Cγ4 expressing cells constitute a major population of γ/δ T cells in thymus and peripheral lymphoid organs in adult mice, but they are only composed of a minor population of γ/δ T cells during fetal and early postnatal life. Vγ1 T cell development can happen in thymus-dependent and thymus-independent manners. Further studies have shown that the antibody 2.11 recognized epitote is located in Cr4 domain.

    FCM

    Mouse

  • 性能

    Liquid

    Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at-20°C or lower. Avoid cycles of freezing and thawing.

    PBS, pH 7.2

    1mg/ml, >95% (by SDS-PAGE)

    Hamster IgG