概述

产品名称：LE/AF Purified Anti-Mouse CD40 Monoclonal Antibody

描述：CD40 is a 48 kD type I transmembrane glycoprotein, also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.

应用范围：FCM

种属反应性：Mouse

性能

形态：Liquid

存储条件：Keep as concentrated solution. Store at 4°C as an undiluted liquid. For extended storage aliquot contents and freeze at -20°C or lower. Avoid cycles of freezing and thawing

存储溶液：PBS, pH 7.2

纯度：1mg/ml, >95% (by SDS-PAGE)

亚型：Rat IgG2a